Life Cycle of Poxviruses Studied

June 21, 2011

The Medical College of Wisconsin received a two-year, $420,750 grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to study the maturation and encapsidation of the DNA chromosome of a specific type of virus called a poxvirus.

Paula Traktman, Ph.D., the Walter Schroeder Professor and Chairman of Microbiology and Molecular Genetics, and senior associate dean for Research Development, is principal investigator for the grant.

There are at least seven types of poxviruses that affect humans; two can be deadly. There is fear that smallpox could be harnessed as a biological weapon by terrorists. Additionally, monkeypox has sickened hundreds. Poxviruses do not replicate like other viruses, and little is known about two proteins that appear to play a large part in the encapsidation process, which is key to the assembly of infectious virus particles.

This research will provide better understanding of this little-known portion of the viral replication process. By understanding the way these viruses spread, we will be able to develop better antiviral therapies to prevent human infection.

About The Medical College of Wisconsin:

The Medical College of Wisconsin is the state’s only private medical school and health sciences graduate school. Founded in 1893, it is dedicated to leadership and excellence in education, patient care, research and service. Approximately 1,200 students are enrolled in the Medical College’s medical school and graduate school programs. A major national research center, it is the largest research institution in the Milwaukee metro area and second largest in Wisconsin. In FY 2009 -10, faculty received approximately $161 million in external support for research, teaching, training and related purposes, of which $148 million is for research. This total includes highly competitive research and training awards from the National Institutes of Health (NIH). Annually, College faculty direct or collaborate on more than 2,000 research studies, including clinical trials. Additionally, more than 1,250 physicians provide care in virtually every specialty of medicine for more than 400,000 patients annually.

 

Community Watch

» Initial Reaction Podcast: Menomonee Falls baseball virtuoso Ty Weber and Big Ten Media Day Updated:  7/29

» 12-year-old Shorewood journalist gets her scoop at the Republican National Convention 7/28

» Whitefish Bay woman takes home grand prize at the Hottest Kitchen Entrepreneur Challenge Updated:  7/27

» Backups of more than 3 miles reported on northbound I-43 at Good Hope 7/27

» 92-year-old Shorewood building will be torn down to make way for North Shore Bank building Updated:  7/27

» Former legislator competing against political organizer for his old Assembly seat 7/27

» Whitefish Bay family's treehouse is a work of art 7/27

» Nicolet High School hires David Coyle as associate principal 7/27

» Shorewood baseball team fought back late in season 7/27

» Lund is new Nicolet girls basketball coach 7/27

» Nicolet baseball team improved despite its youth 7/27

» Kasmarick adjusting to life as Whitefish Bay athletic director 7/27

» Social media story on the storms rolling through Milwaukee area 7/21

» Milwaukee's first surf shop rides into Shorewood Updated:  7/21

» Rock climbing wall, trampolines might come to Brown Deer business park Updated:  7/20

» Whitefish Bay baseball team ends Shorewood magic with regional win 7/20

» Nicolet baseball team goes down fighting in regional loss to Kewaskum 7/20

» Whitefish Bay's Rybakowicz shuts out Brown Deer in regional semi 7/20

» Initial Reaction Podcast: Wisconsin Badgers football, WIFCA All-Star game 7/20

» West Bend West's Burns beats Whitefish Bay baseball team on mound, at plate in sectional 7/20

» Maslowski oversaw creation of nine tax incremental financing districts 7/19

» Maslowski transformed Glendale in impactful career as city administrator 7/19

» Development is off the table in Wilson Drive discussions 7/19

» Debbie Roesner appointed to Fox Point-Bayside School Board 7/19

» Bublr makes push for extra bike rental stations in Shorewood 7/18

View All Posts Got a tip? Welcome rss

Best Summer Ever

 

We've made it easy for you to get out and go this summer. From hitting the trails for a bike ride or walk, to where to find beer gardens in the area, to the best places to swim in Waukesha County to the best summer drinks and summer reads, check out our 2016 summer guide.

Advertisement

Advertisement

Advertisement

CONNECT